I like audiences to be between 20,000 and 50,000. Any larger than that, and you’re unlikely to learn much from the performance of any single audience. When faced with a larger audience size, I like to break it up into multiple smaller segments and split them up by seniority or geography. This allows me to measure the differences in engagement based on facets that help me better craft meaningful messages and content.
Source: LinkedIn Ads: How to target your ideal prospect, every time – Marketing Land